91119 Neuroscience & Musculoskeletal (1)

Course Description

This course integrates the basic sciences into a study of neuroscience and behavior in both health and disease conditions of the anatomy, physiology, pharmacology, microbiology and pathology of the peripheral nervous system, neuroanatomy. Topics covering are neurophysiology, neurological correlation, neuropharmacology, neuropathology, microbiology, human behavior and biochemistry. Also this course is designed to provide a basic knowledge and understanding of the structure, function of the nervous system, and musculoskeletal system, biochemical basis of human behavior, as well as the pathological basis of neurological and mental disorders. Fundamental principles of anatomy, physiology, pharmacology, pathology, microbiology and human behavior will be applied to pathological situations to distinguish the clinical basis for central nervous system disorders and knowledge about bones, joints muscles, tendons, ligaments, skin and associated soft tissues related to clinical manifestations of diseases.

Learning Objective

  • At the end of the course the student shall be able to :
  • 1) Outline the general organization of the nervous system and Describe the gross features of the human central nervous system (brain and spinal cord).
  • 2) Discuss chemical synaptic transmission in terms of mechanisms, functions, and properties, and drugs modulating synaptic transmission.
  • 3) Describe brain coverings, cerebrospinal fluid (CSF), and blood supply of the central nervous system.
  • 4) Define the structural basis, physiological, and pharmacological properties of the pathways that t ransmit sensory and motor information in the central nervous system.
  • 5) Describe pathogens that infect the central nervous system and the specific diseases related to the infection process and the pathological changes in central nervous system tissue that underlies various neurological diseases.
  • 6) Describe the principles that guide our understanding of human behavior and the biochemical basis of various behavioral disorders.
  • 7) Correlate lesion sites at specific levels of the central nervous system with neurological and pathological findings of various neurological disorders.
  • 8) Describe the pharmacology of drugs employed in the management of various mental and neurological disorders
  • 9) Learn the mechanisms of sensing the various environmental stimuli.
  • 10) Analyze the structures conveying information to/from the central nervous system and understand the biochemical events taking place within this system.
  • 11) Be able to comprehend how drugs modify the functions of this system and explain the various possibilities where things can go wrong in different parts of the system.
  • 12) Know common infections affecting this system and Be able to explain symptoms, signs, investigations and forms of treatments of nervous system’s anomalies.
  • 13) Identify and describe bones, muscles and joints of the upper, lower limbs and the vertebral column and give nerve supply and actions of the muscles associated with them.
  • 14) Describe normal development and congenital abnormalities of limbs and vertebral column.
  • 15) Understand the metabolism and the biochemical and molecular basis of diseases affecting muscles and bones.
  • 16) Describe the mechanism of muscle contraction and understand the mechanism of action, pharmacokenetics and therapeutic use and adverse effects of drugs that affect the musculo-skeletal system and the skin.
  • 17) Understand the pathogenesis and pathological features of infections and diseases that affect bones, joints, muscles, soft tissue and the skin.
  • 18) Understand the epidemiology and control of the common injuries that may affect the humanmusculo-skeletal and skin.
  • 19) Describe the macroscopic and microscopic features of the skin and subcutaneous tissues.
  • 20) The biochemical processes of normal skin and subcutaneous tissues
  • 21) Describe the commensals and pathogenic microbes affecting the skin, subcutaneous tissue and musculoskeletal system.
  • 22)The pathological changes that occur in the skin, and the etiology, pathogenesis and pathologic features of selected major diseases of the skin



Books for this Course

  • Principles of Neurosurgery
  • Setti S. Rengachary& Robert H. Wilkins
  • Handbook of Neurosurgery
  • Mark S. Greenberg

Times Offered

  • September 2014
  • January 2015